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Open access Sep 2026

Molecular Characterization of Sclerosing Nevi With Pseudomelanomatous Features.

INTRODUCTION Sclerosing nevi with pseudomelanomatous features (SNPF) are rare melanocytic lesions characterized by a distinctive trizonal architecture, created by lateral shouldering of the junctional component and nests of melanocytes within the dermis that can histologically mimic melanoma, posing a diagnostic dilemm...

Zachary Corey, Mckinzie Johnson, John Fowler et al. · 0 citations
Review Open access Sep 2026

Landscape of approaches for streamlining pre-analytical and early analytical variables for solid tumor next-generation sequencing: A Genomics Organization for Academic Laboratories consortium report

The scope of pre-analytical and early analytical methods used in clinical molecular laboratories can have vast effects on the quality and turnaround time for solid tumor next-generation sequencing assays. To learn more about various approaches, a survey of 24 academic laboratories within the Genomics Organization for A...

M. David, Jennifer J. D. Morrissette, N. Brown et al. · 0 citations
Review Aug 2026

Clinical Variant Interpretation with the Integrative Genomics Viewer (IGV) for Molecular Pathologists.

The integrative genomics viewer (IGV) is a pivotal tool in clinical genomics, enabling the visualization and interpretation of complex sequencing data. Bringing clinical knowledge to bear with visual evaluation of sequencing results is the primary means by which molecular pathologists and other professionals assess and...

E. Halper-Stromberg, Suguna P. Narayan, V. Laufer et al. · 0 citations
Review Jul 2026

Next-generation sequencing reporting practices among the Genomics Organization for Academic Laboratories (GOAL) institutions: Current state and opportunities for harmonization.

Tumor next-generation sequencing (NGS) is widely used to refine diagnosis and identify therapy targets. However, reporting criteria, schemas, and formats vary greatly which can affect uniformity of clinical cancer care. With the aim of promoting harmonization, the current state of NGS reporting practices was profiled a...

Celeste C. Eno, R. Sompallae, Daniel Jones et al. · 0 citations

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