Neuroprotective Action of Agonists and Modulators of A1 Adenosine Receptors Upon Hyperexcitation: Mechanism of the Antiepileptic Activity and Role of Neuron‐Glial Interaction
Hyperexcitation of neuronal networks is a key mechanism underlying excitotoxic neuronal death in conditions such as epilepsy, ischemic stroke, and traumatic brain injury. Given the inhibitory role of Gi‐coupled receptors, A1 adenosine receptors (A1Rs) represent promising targets for neuroprotective and anticonvulsant t...