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Author

D. Arya

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Aug 2026

Activity of Thiourea-Linked Diamidines against Multidrug-Resistant Staphylococcus aureus.

There was a lack of resistance observed with the PAs, compared to the fairly rapid and stable resistance occurrence for drugs commonly used to treat S. aureus infection, reflecting the potential of such compounds as potential new tools to optimize and combat the menace of drug-resistant S. aureus.

Yi Jin, S. Story, J. Chamberlin et al. · 0 citations
Aug 2026

Tobramycin-Peptide Nucleic Acids Synergize with Polymyxin B and Other Bioactive Compounds to Inhibit Growth of Gram-Negative Bacteria

Resistance studies demonstrate that the TOB-PNA conjugate, both alone and in combination with PMB, maintains antibacterial activity over prolonged exposure, suggesting a higher barrier to resistance evolution than conventional TOB treatment.

S. Story, Sarah L. Wicks, Sayantan Bhaduri et al. · 0 citations

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