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D. Baker

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Open access Aug 2026

Protein design to broadly reprogram engineered T cell function

OutLAST Regulators are designed proteins that reprogram critical T cell signaling pathways to enhance functional persistence and are implemented as compact genetic modules compatible with standard viral vectors and cell therapy manufacturing processes, creating a powerful platform for programming new functions into enhanced cell and gene therapies.

S. Boyken, Sean A Merillat, Robert A. Langan et al. · 0 citations