Aug 2026
Nonhuman Primate Genomes Have Limited Relevance for Evaluating Human CRISPR Off-Target Effects.
The results highlight the limitations of NHPs for the study of human CRISPR spacer specificity and contextualize human risk informed by these studies, and highlight the risks associated with off-target editing events.
Laura Blaha, M. Bosinger, D. Bodian et al.
· Human Gene Therapy · 0 citations