Author

D. Bzdok

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#small language model Review Open access Sep 2026

Paired neuronal-haemodynamic neurovascular coupling measures and cognitive performance in vascular pathology: protocol for a systematic review and meta-analysis

Neurovascular coupling (NVC) links neuronal activity to haemodynamic responses. Altered NVC may contribute to cognitive impairment in vascular pathology, but evidence is limited by inconsistent definitions and by the conflation of paired neuronal–haemodynamic NVC measures with haemodynamic-only, model-derived, or...

V. Abramova, Marta Estrada, Veronica Egovtseva et al. · Systematic Reviews · 0 citations

Open access Jul 2026

Parent-of-origin effects in Alzheimer’s liability dissociate neurocognitive and cardiovascular traits in at-risk individuals

Summary Alzheimer’s disease (AD) has a higher prevalence in women than men and is more frequently inherited from mothers than fathers. Yet, while neuroimaging and biomarker studies link maternal family history to stronger AD-related alterations, epidemiological studies suggest that paternal history confers comparable o...

Chloé Savignac, Frédéric St-Onge, S. Villeneuve et al. · Cell Reports Medicine · 0 citations

Open access Aug 2026

Mapping Alzheimer’s neuropathology signatures to the whole brain transcriptome using machine learning data-fusion

In Alzheimer’s disease (AD), misfolded proteins emerge across the entire brain in structured, yet not rigid, spatiotemporal patterns. Yet, a systematic bias of single-cell genomics toward sampling mostly cortical tissue limits our understanding of the whole-brain transcriptomic vulnerability to AD. Here, we develop a m...

Anwesha Bhattacharya, Chloé Savignac, Liam Hodgson et al. · bioRxiv · 0 citations