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D. Cannella

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Open access Aug 2026

Divergent SAGA complexes shape the Toxoplasma transcriptome for lytic cycle progression and host interaction

Histone acetylation governs Toxoplasma gondii gene expression, developmental plasticity and virulence, yet the organization and deployment of its acetyltransferase machinery remain poorly understood. Here, we show that T. gondii rewired this process using a plant-like system built around the acetyltransferase TgGCN5b,...

D. Cannella, Belén Pachano, Martina Shahinas et al. · 0 citations

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