Sep 2026
Germline EGFR T790M mutation and lung cancer risk.
J. LoPiccolo, S. Micheletti, Jingchunzi Shi et al.
· Science · 0 citations
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Open access
Jul 2026
Genetic architecture of lung cancer revealed by common and rare variant analyses across population-scale biobanks.
Genome-wide association studies have predominantly implicated common variants in lung cancer susceptibility, whereas the contribution of rare non-coding variation remains incompletely defined. This study comprised 52,550 cases and 1,617,173 controls across three whole-genome sequencing (WGS) cohorts (UK Biobank, the 10...
Jingyi Zhao, Lei Qiao, Yixin Zhang et al.
· npj Precision Oncology · 0 citations
Open access
Jul 2026
Germline determinants of risk and molecular subtype in young-onset lung cancer
A complex germline architecture underlying susceptibility and molecular subtype in young-onset lung cancer is delineated, consistent with additive risk from rare and common variants.
J. LoPiccolo, Ryan L. Collins, Noah Fields et al.
· medRxiv · 0 citations