Author

D. de Vega

2 papers indexed here

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Review Open access Sep 2026

Beyond the blood-brain barrier: humanised mice, the missing link in glioblastoma research.

Glioblastoma (GBM) remains a major challenge in neuro-oncology, associated with a high rate of mortality despite decades of intensive research and therapeutic advancements, underscoring the urgent need for innovative preclinical platforms that can more accurately recapitulate the biological and pathological features of...

Reza Shirazi Nia, Jian Lu, D. de Vega et al. · Oncogene · 0 citations

Open access Aug 2026

A Regulatory Element in the Intrinsically Disordered C-Terminal Region of LMTK3 Modulates Its Kinase Domain Interactions and Breast Cancer Phenotypes

Together, these findings identify a previously uncharacterised regulatory element within the LMTK3 C-terminus and support a model in which Ser1258 phosphorylation modulates kinase domain interactions and LMTK3-driven oncogenic functions in BC.

Andrea Lauer Betrán, A. Agnarelli, Mark Samuels et al. · Cells · 0 citations