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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

D. Einstein

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2 papers indexed here

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Open access Aug 2026

A Phase II Study of Berzosertib in Combination with Carboplatin Compared with Docetaxel with Carboplatin in Metastatic Castration-Resistant Prostate Cancer

Abstract Purpose: Inhibitors of the ataxia-telangiectasia and Rad3-related (ATR) protein kinase, a critical component of the DNA damage repair response, have synergistic anticancer activity with platinum compounds in preclinical models. We therefore conducted a phase II study of the ATR inhibitor berzosertib + carbopla...

A. Choudhury, C. Zhong, Wan-Ling Xie et al. · 0 citations
Open access Aug 2026

Tumor-adjacent B cell infiltration stratifies recurrence risk in localized prostate cancer

Background: Biochemical recurrence (BCR) occurs in 20-40% of men after radical prostatectomy. Existing postoperative recurrence risk tools based on PSA and pathology are clinically useful but show only moderate and variable discrimination, highlighting the need for biomarkers that improve risk stratification and conseq...

B. Wang, S. Mukherjee, A. Baj et al. · 0 citations

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