Author

D. Engel

2 papers indexed here

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Open access Sep 2026

Spatial transcriptomics reveal impaired metabolic liver zonation in acute-on-chronic liver failure.

BACKGROUND AND AIMS Extrahepatic organ failures are key determinants of acute-on-chronic liver failure (ACLF). While the role of systemic inflammation and mitochondrial dysfunction in the pathogenesis of ACLF is well known, the contribution of the liver itself is less understood. We therefore performed transcriptome an...

Mona-May Langer, H. Stadler, M. Mannewitz et al. · JHEP Reports · 0 citations

Open access Aug 2026

CX3CR1 Modulates Migration of Resident Microglia Towards Cortical Laser‐Induced Lesions

Microglia are innate immune cells of the central nervous system (CNS). They extend their processes and migrate toward injuries in vivo. However, how the fractalkine receptor (CX3CR1) influences microglial migration remains unknown. Label‐free proteomic profiling predicted changes in Ras homology family (RHO)‐signaling...

Jens Wagner, Henrike Antony, C. Hoyer et al. · Glia · 0 citations