Early-life development of the gut microbiome plays a critical role in shaping host physiology. However, a comprehensive understanding of how diet, microbial community assembly, functional capacity, and host intestinal maturation axes evolve and coordinate over time remains lacking. Most studies focus on a single...
Carta Giacomo, Feng Xian, Daniel Malzl et al.· Microbiome· 0 citations
This perspective highlights recent advances in multi-omics microbiome research, outlines key obstacles in data integration and metadata harmonization, and proposes a collaborative roadmap for scalable, FAIR-compliant multi-omics investigations and potentially disruptive Artificial Intelligence advances.
T. Van Den Bossche, Eunice Lazau, Velma T. E. Aho et al.· Nature Communications· 0 citations
DIA- and Slice-PASEF show strong quantitative reproducibility, reduced ratio compression, and consistent species-abundance scaling, while functional profiling reveals expanded annotation depth, and the two highest-scoring methods, DIA- and Slice-PASEF, capture concordant host and microbial responses.
Feng Xian, Goran Mitulović, Ranjith Kumar Ravi Kumar et al.· Nature Communications· 0 citations
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