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Open access Aug 2026

Image-guided low-intensity focused ultrasound neuromodulation: acoustic targeting optimization and functional validation in a reward circuit model.

OBJECTIVE To develop and validate an ultrasound-guided low-intensity focused ultrasound (USg-LIFU) platform for subject-specific deep-brain neuromodulation and test whether ventral tegmental area (VTA) targeting modulates alcohol-related behaviour in a mouse model of alcohol use disorder. METHODS USg-LIFU uses ultras...

Sudeep Mondal, Hao Yang, D. Gulick et al. · 0 citations
Sep 2026

Gene expression and brain pathology at the early stages of bilateral chronic cerebral hypoperfusion in the female mouse brain.

Chronic cerebral hypoperfusion (CCH) is a major risk factor for neurodegenerative diseases, including vascular dementia (VD). It is well documented that sex differences account for variability in progression and outcomes in cerebrovascular pathophysiology and dementia risk. Despite extensive study of VD, most mechanist...

Sarra Limam, A. Mazzarella, Randall Hernandez-Jimenez et al. · 0 citations

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