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Author

D. Horst

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Open access Aug 2026

Mesenchymal R-spondin 3 promotes an immunogenic tumor microenvironment with adaptive immune resistance in human gastric adenocarcinoma.

Positive associations between RSPO3 expression and inflammation suggest that RSPO3 signaling contributes to shaping the immune microenvironment of human intestinal-type GC, a phenotype specific to intestinal-type GC.

Anne-Sophie Fischer, Alexander Arnold, Hilmar Berger et al. · 0 citations
Open access Jul 2026

Immune evasion in locally advanced mismatch repair-deficient microsatellite instability-high colorectal cancer: Reduced T-cell infiltration and upregulation of epithelial IDO1 expression

The overall immunogenicity and prognostic relevance of immune markers in dMMR/MSI-H CRC depend on tumor stage, and immune profiling could be used for early-stage patient stratification and also suggests the potential benefit of early immunotherapeutic intervention.

Sabina Niyazova, C. Sers, H. Bläker et al. · 0 citations

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