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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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D. Hu

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Open access Sep 2026

ECC-MR: an error-correcting-code framework for robust Mendelian randomization and pleiotropy decoding on correlated instruments

Mendelian randomization (MR) uses genetic variants as instrumental variables for causal inference, but its validity is often undermined by horizontal pleiotropy and linkage disequilibrium (LD) among instruments, which current methods typically address by discarding correlated or outlying variants. Here we present ECC-M...

J. Jiang, D. Hu, Q. Zhang et al. · 0 citations

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