Open access
Aug 2026
Coordinated suppression of lectin complement pathway effectors and upregulation of SERPING1 defines a thrombo-inflammatory regulatory signature in Acute Coronary disease
Findings identify SERPING1, and by extension the MASP–SERPING1 axis, as a candidate biomarker and therapeutic target meriting prospective, matched-cohort validation, with protein-level confirmation of the acute-phase transcriptional response captured here.
Managalli G. Manohara, Veena Nanjappa, D. Javaregowda et al.
· Molecular Biology Reports · 0 citations