A Biallelic ITGA10 Variant as a Candidate for Inherited Thrombocytopenia: Insights From a Whole-Exome Sequencing Cohort.
Findings support ITGA10 as a novel candidate gene for inherited thrombocytopenia and suggest that disruption of the ITGA10-ITGB1 integrin complex may contribute to abnormal platelet homeostasis and cytoskeletal organization.