Mechanisms aimed at recovering from heat-induced damage are closely associated with the organism's ability to survive extreme temperature exposure. In such a scenario, we show that autophagy, as a cytoprotective mechanism, ensures recovery and viability after induced heat stress in Saccharomyces cerevisiae. Our finding...
Dimitra Dialynaki, Yuxiang Huang, D. Klionsky· Autophagy· 0 citations
Despite the research progress of the past decades, the prognosis for pancreatic ductal adenocarcinoma remains poor. Identifying novel targets and exploring the underlying mechanisms is therefore of great importance. ELF3 (E74 like ETS transcription factor 3) is a member of the E-twenty-six (ETS) family and previo...
Yu-Ru Shang, Pingping Zhang, Yanhui Yang et al.· Journal of Experimental &...· 0 citations
Biomolecular phase separation has emerged as a key organizing principle in macroautophagy (hereafter autophagy). In mammalian cells, phase‐separated condensates not only serve as substrates for selective degradation, but also act as dynamic platforms for cargo recognition, signaling integration, and autophagosome assem...
Yuan-Qiang Lin, Mingran Dai, En-Yong Dai et al.· Advancement of science· 0 citations
Macroautophagy/autophagy is a well-established homeostatic mechanism that contributes to the integrity of multiple regulatory biological activities including but not limited to the gastro-intestinal tract and cognitive integrity. Autophagy also plays a central role in tissue regeneration, metamorphosis and development...
Ahmed M. Elshazly, Aya A Elzahed, Shady Allam et al.· Autophagy· 0 citations
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