Sep 2026
Hybrid risk scores integrating polygenic and clinical variables for endometriosis prediction
Combining the PRS with symptom and comorbidity data gave the best discrimination compared to solely a well-powered, multi-ancestry PRS as a predictor of endometriosis, and points to symptom-based phenotyping, molecular subtyping, and external validation as priorities.
O. Goroshchuk, D. Koller
· medRxiv · 0 citations