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Author

D. Krüger

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Open access Sep 2026

Innervated human cardiac muscle model reveals sympathetic drivers of KCNH2-associated arrhythmias

Cardiac autonomic neurons regulate contractility. Autonomic nervous system dysregulation can cause sympathetic overdrive, leading to heart failure, and fatal arrhythmias. Here, we introduce innervated engineered human myocardium (iEHM), a model of neuro-cardiac junctions, constructed by fusing sympathetic neuronal orga...

L. V. Schneider, Michael Gani Setya, Guobin Bao et al. · 0 citations
Open access Jul 2026

The lncRNA Gm16685/MITA1 modulates inflammatory astrocyte reactivity through PCBP2 associated regulation of IKKβ signaling

These findings identify Gm16685/MITA1 as a conserved lncRNA regulator of astrocyte reactivity and suggest that non-coding RNA dependent control of RNA binding proteins contributes to inflammatory signaling in neurodegenerative disease relevant contexts.

Ulrike Fuchs, Sophie Schröder, T. Pena et al. · 0 citations

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