D. Lee

3-Methoxychrysazin suppresses RANKL-induced osteoclastogenesis by modulating Notch2 signaling.

Bone homeostasis is maintained by a delicate balance between osteoblast and osteoclast activity, and disruption of this equilibrium leads to bone loss and associated disorders. Oxidative stress and dysregulation of key signaling pathways, such as Notch2 and NF-κB, play pivotal roles in promoting osteoclastogenesis and...