BACKGROUND
Bipolar disorder (BD) studies consistently implicate the ventral prefrontal cortex (VPFC) in association with suicidal behaviors. A suicidal behavior polygenic risk score (PRS) can now be computed to test whether elevated genetic risk for suicidal behavior is associated with variation in VPFC gray matter and...
Noa Katz Shroitman, D. Levey, Brian P. Pittman et al.· Bipolar Disorders· 0 citations
Genomic studies have improved our understanding of posttraumatic stress disorder (PTSD) biology. Epigenetic differences in DNA methylation can reflect environmental influences, which are critical in PTSD etiology, and may additionally differentiate between PTSD cases and controls or distinguish severity of PTSD symptom...
S. Beck, D. Levey, M. Galimberti et al.· medRxiv· 0 citations
Abstract Background Genetic and environmental factors, and psychiatric traits, contribute to risk for alcohol use disorder (AUD) and other substance use disorders (SUDs) and traits. Weighing the importance of the different kinds of contribution to risk is important in understanding risk prediction – which may be import...
P. Na, J. Deak, D. Levey et al.· International Journal of Neu...· 0 citations
Migraine is a leading cause of disability, yet preventive treatment remains largely empirical despite the availability of several mechanistically distinct therapies. Genetic data can clarify mechanisms and therapeutic hypotheses when association signals are integrated with molecular and clinical data. We meta-analyzed...
C. Overstreet, M. Galimberti, K. Harsan et al.· medRxiv· 0 citations
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