Author

D. M. Tobin

2 papers indexed here

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Open access Sep 2026

Polyketide synthase 12 is an in vivo essential source of novel mycolyl lipids in Mycobacterium tuberculosis

Mycobacterium tuberculosis (Mtb) is a major pathogen worldwide that infects and transmits only among humans, yet nearly all in vivo virulence research occurs in non-human hosts. To overcome this central challenge in tuberculosis research, we leveraged a dataset of more than 50,000 sequenced isolates to identify Mtb gen...

Gregory H. Babunovic, Sanne van der Niet, M. Gontijo et al. · bioRxiv · 0 citations

Open access Aug 2026

Deep sequencing reveals subpopulation dynamics associated with treatment failure in a rare non-tuberculous mycobacterial infection

Background Nontuberculous mycobacteria (NTM) are an increasingly common group of pathogens that remain challenging to diagnose and treat effectively. The lack of standardization of NTM management, from identification to antibiotic resistance prediction, results in imperfect correlations between treatment and outcomes....

A. Menon, C. Mariner-Llicer, A. M. Xet-Mull et al. · medRxiv · 0 citations