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Author

D. Manu

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Open access Aug 2026

Extracellular Vesicle-Associated miRNA in Multiple Sclerosis Subtypes: Differential Profiles in Secondary Progressive Disease and the Effect of One-Year Siponimod Treatment

Preliminary observations should be interpreted with caution, given the exploratory nature and modest cohort size, but the selective downregulation of EV-miR-223-5p and EV-miR-155-5p may tentatively suggest candidate molecular signatures warranting further interrogation.

Oana Vrînceanu, S. Maier, D. Manu et al. · 0 citations
Open access Aug 2026

Plasma-Derived Extracellular Vesicle microRNAs in Multiple Sclerosis: An Exploratory Case-Control Study on Phenotypic Discrimination

Findings suggest EV-miR-223-5p as a candidate marker of the progressive phenotype and EV-miR-155-5p as a disease indicator, which is hypothesis-generating and requires validation in larger, longitudinal cohorts.

Oana Vrînceanu, D. Manu, S. Maier et al. · 1 citation

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