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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

D. Martin

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Open access Jul 2026

Complex intra-host SARS-CoV-2 evolution following monoclonal antibody pre-exposure prophylaxis

Sotrovimab pre-exposure prophylaxis in an immunocompromised patient did not prevent SARS-CoV-2 infection, and was selected for resistant mutation E340D, with unexpected fitness consequences across non-receptor binding domain spike regions.

K. Kamelian, D. Pascall, Mei-Jun Cheng et al. · 1 citation

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