Author

D. Matuskey

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Open access Aug 2026

Preliminary evidence of neuroimmune system disruption in opioid use disorder: Findings from a pilot PET TSPO imaging study

Background Preclinical and postmortem human studies demonstrate significant opioid-related alterations in the neuroimmune system. However, studies investigating the neuroimmune system in living people with opioid use disorder (OUD) are lacking, thereby motivating this pilot study. Methods Individuals with OUD (n = 6; D...

E. Woodcock, D. Matuskey, Yi-Yun Huang et al. · Brain, Behavior, & Immunity... · 0 citations

Open access Sep 2026

Alterations in relative perfusion and synaptic patterns in Parkinson’s disease using dynamic SV2A PET

Purpose Dynamic [11C]UCB-J PET can simultaneously provide information about synaptic density and relative perfusion in Parkinson's disease (PD). We investigated whether these complementary biomarkers could explain a higher percentage of motor symptom severity variation in PD and inform other PD-specific physiological a...

P. Honhar, Sule Tinaz, F. Sadabad et al. · medRxiv · 0 citations

Sep 2026

Exploratory imaging in SWEDD: Insights from dopaminergic PET, synaptic density PET, and volumetric MRI.

OBJECTIVE Scans Without Evidence of Dopaminergic Deficit (SWEDD) refers to individuals with Parkinsonian symptoms but no presynaptic dopaminergic deficit on dopamine transporter (DAT) imaging. Given its likely heterogeneity, we used a multimodal imaging approach to compare SWEDD with Parkinson's disease (PD) and health...

Faranak Ebrahimian Sadabad, Tommaso Volpi, Sule Tinaz et al. · Parkinsonism & Related Disor... · 0 citations