Genetic regulation of biosynthesis and resistance to redox-active phenazines in Burkholderia spp.
This study identified genes involved in phenazine production, regulation, and resistance in Burkholderia lata 383, a member of the B. cepacia complex, which produces dimethyl 4,9-dihydroxy-1,6-phenazinedicarboxylate and characterized the transcriptomes of phenazine and quorum-sensing (QS) mutants of B. lata 383.