D. Mazzotti

Zero-Shot Extraction of Structured Clinical Data from Free-Text CT Reports Using Foundational Large Language Models

Introduction. Large language models (LLMs) are being explored for multiple applications in medical research, including medical text classification. Authors of the study evaluated the performance of three off-the-shelf LLMs in classifying unstructured free-text CT pulmonary angiography reports for pulmonary embolism (PE...

Prediction of Obstructive Sleep Apnea Using Variational Autoencoder-Derived Features From 12-Lead ECG

BackgroundObstructive sleep apnea (OSA) is a highly prevalent sleep disorder. Major risk factors include obesity, older age, and male sex. Given the well-established association between OSA and cardiovascular disease, markers of cardiovascular health derived from electrocardiography (ECG) may help identify individuals...

Predicting One-Year CPAP Adherence and Use Trajectories Utilizing Baseline and Early Use Data

Machine Learning Models Using Electronic Health Record Data to Predict Obstructive Sleep Apnea

Real-world effectiveness of early nirmatrelvir/ritonavir initiation after COVID-19 diagnosis in outpatient setting against severe illness, hospitalization, death, and long COVID in N3C

Evaluated the real-world effectiveness of NMV-R in preventing severe illness, hospitalization, death and long-COVID in a large nationwide cohort of outpatients with COVID-19 and found it overall effective at preventing the risk of severe acute outcomes including hospitalization and death, as well as long COVID.

COVID-19 vaccination timing, relative to acute COVID-19, and subsequent risk of long COVID

It is found that COVID-19 vaccination was protective against Long COVID, and a significant waning of this protection within seven months after vaccination was observed.