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Author

D. Nicholas

2 papers indexed here

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Open access Aug 2026

Endocrine-Adapted Pituitary Macrophages Regulate Gonadotropin Secretion through CXCL5-CXCR2-MAPK Signaling

Chronic inflammation disrupts hormonal balance in the Hypothalamic-Pituitary-Gonadal (HPG) axis, contributing to reproductive disorders. While immune cells in the hypothalamus and ovaries have been extensively studied, their impact on the pituitary remains largely unexplored. Our research identifies pituitary macrophag...

Z. Del Mundo, J. Ha, Lily Zhou et al. · 0 citations
Open access Aug 2026

TREM2 plays a critical role in innate immune defense against acute Toxoplasma gondii infection by promoting macrophage antimicrobial activities

A critical role is demonstrated for TREM2 in the early antimicrobial immune response to T. gondii infection by limiting parasite expansion, dissemination, and pathological inflammation in the infected host.

Hannah Z. Debray, Dillon Cheng, L. A. Ayala et al. · 0 citations

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