Author

D. Patle

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Review Open access Sep 2026

Target‐Based Antitubercular Drug Discovery: Scaffold Diversity and SAR Trends of Small Molecules Against Mycobacterium Tuberculosis

Tuberculosis remains a major infectious disease, and the increasing incidence of multidrug‐resistant Mycobacterium tuberculosis continues to limit current treatment options. This review summarizes recent medicinal chemistry efforts directed toward six important M. tuberculosis targets: InhA, DprE1, MmpL3, QcrB, DNA gyr...

R. Kalita, K. Kolekar, Sachin Kumar Singh et al. · Archiv der Pharmazie · 0 citations

Review Open access Aug 2026

Spirooxindole Derivatives as Emerging Scaffolds in Drug Discovery: Synthetic Strategies, Structure–Activity Relationship, and Biological Activities

The recent patents, especially on MDM2 inhibitors and other anticancer agents with nanomolar potency, provide further evidence for the continued interest in spirooxindole‐based drug discovery.

R. Kalita, Sarbanga Bezbaruah, D. Patle · ChemMedChem · 0 citations