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Author

D. Plante

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2 papers indexed here

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Sep 2026

An examination of the effect of dual task on gait in Parkinson's disease and REM sleep behavior disorder.

BACKGROUND Gait variability is a hallmark of Parkinson's disease (PD) and has been linked to cognitive deficits and fall risk. Rapid eye movement sleep behavior disorder (RBD) is a strong predictor of synucleinopathies, yet evidence for gait changes in RBD is inconsistent. Performing a dual task increases gait variabil...

Catherine L. Gallagher, M. Haebig, Ananya Heroor et al. · 0 citations
Aug 2026

Safety, tolerability, and efficacy of alixorexton, a selective orexin 2 receptor agonist for narcolepsy type 1 (Vibrance-1): a randomised, double-blind, placebo-controlled, phase 2 trial.

BACKGROUND The clinical potential of orexin 2 receptor (OX2R) agonism for improving measures of wakefulness and cataplexy in patients with narcolepsy type 1 has been described in a phase 2 study. Here, we aimed to evaluate the safety, tolerability, and efficacy of alixorexton, another oral OX2R agonist, in narcolepsy t...

G. Plazzi, Ronald R. Grunstein, Emmanuel Mignot et al. · 1 citation

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