The transcriptional coactivators p300 and CREB-binding protein (CBP) integrate chromatin remodeling, enhancer activity, lysine acetylation, immune signaling, and tumor-suppressor control, making them recurrent targets of viral proteins. This narrative review examines p300/CBP at the virus-cancer interface, prioritizing...
A. Atoom, J. Rizaev, D. Polatova et al.· Cancer Treatment and Researc...· 0 citations
Oncolytic virotherapy has evolved from a tumor-selective cytolytic strategy into a programmable immunotherapeutic platform that reshapes the tumor microenvironment (TME). Oncolytic viruses (OVs) selectively infect malignant cells, induce immunogenic cell death, release tumor antigens, and activate innate and adaptive i...
A. Atoom, J. Rizaev, D. Polatova et al.· Cancer Treatment and Researc...· 0 citations
Breast cancer (BC) constitutes the most prevalent malignancy globally, with an incidence of approximately 80%–85% for invasive ductal carcinoma (IDC) and 10%–15% for invasive lobular carcinoma (ILC), and a persistently high mortality and morbidity rate. Although IDC and ILC originate from distinct cellular lineages (du...
Muslem Nuseir, Farrukh Ismatov, A. Abdulqader et al.· IUBMB Life - A Journal of th...· 0 citations
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