Maternal Characteristics, First-Trimester Biomarkers and Cell-Free DNA Fetal Fraction: A Single-Center NIPT Cohort over Ten Years
The fetal fraction (FF) of cell-free DNA determines the reliability of non-invasive prenatal testing (NIPT); whether first-trimester placental biomarkers add information beyond maternal factors is unclear. We linked NIPT samples from a single fetal medicine center over ten years (1162 pregnancies) to first-trimester sc...