Author

D. Riemann

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Open access Oct 2026

Coordinated Brain-Heart Dynamics During Human NREM Sleep

Communication between the brain and cardiovascular system is increasingly recognized as a fundamental determinant of health, yet the mechanisms coordinating neural and cardiac rhythms remain poorly understood. Sleep provides a unique physiological state for investigating neurovisceral integration because cortical slow...

C. Mikutta, Miriam Planta, Thomas Koenig et al. · bioRxiv · 0 citations

Review Sep 2026

Dose-response meta-analysis of dual orexin receptor antagonists on sleep parameters and implications for orexin-mediated arousal.

OBJECTIVE The dose-response profiles of dual orexin receptor antagonists (DORAs) remain incompletely characterized, despite their wide usage in insomnia disorder. We aimed to define relationships between dose, sleep parameters and sleep-architecture outcomes for daridorexant, lemborexant, and suvorexant. METHODS We s...

Claudio Caiazza, L. Palagini, C. Toni et al. · Sleep Medicine · 0 citations