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Author

D. S. Palmer

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2 papers indexed here

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Open access Oct 2026

Rank-based integration identifies convergent disease mechanisms across omics

The rapid growth of omics studies offers new opportunities to uncover disease mechanisms, yet findings from individual studies or single omics may be influenced by cohort-, platform– and layer-specific variation. Integrating evidence across studies and omics layers can reveal robust biological signals that are reproduc...

Z. Qiu, D. Palmer, L. Jostins et al. · 0 citations
Open access Aug 2026

Deviations from genetic additivity driven by rare variants at biobank scale

Additive genetic models are the default for genome-wide association studies, but deviations from additivity are crucial for understanding disease mechanisms and therapeutic responses. Yet existing methods for testing nonadditivity are computationally infeasible for large-scale analysis or rely on Hardy-Weinberg assumpt...

Frederik H. Lassen, S. S. Venkatesh, N. Baya et al. · 0 citations

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