Cardiorenal syndrome describes the clinical consequences of the bidirectional influence that cardiac and renal dysfunction exert on each other—a domain in which single-organ care proves insufficient. A 2024 meta-analysis estimated the pooled prevalence of chronic kidney disease among patients with heart failure at 49%....
G. Gembillo, V. Calabrese, L. Soraci et al.· Medicina· 0 citations
In many immune-mediated kidney diseases, tissue injury is driven by dysregulated B-cell immunity, with autoantibodies and complement acting as key effectors at the glomerulus. Corticosteroids and conventional immunosuppressants control these diseases only in part, and they do so at the price of cumulative toxicity and...
L. Visconti, L. Soraci, Lorenzo Lo Cicero et al.· Future Pharmacology· 0 citations
INTRODUCTION
FSGS is a histological convergence point for biologically distinct conditions: primary immune-mediated, genetic, and secondary adaptive forms, each with its own pharmacological logic. ACE inhibitors and angiotensin receptor blockers have anchored its management for three decades on evidence drawn predomina...
G. Gembillo, Chiara Casuscelli, A. L. La Spada et al.· Expert Opinion on Pharmacoth...· 0 citations
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