Neuromodulation methods in the treatment of drug-resistant epilepsy: history, clinical efficacy and unresolved issues. A literature review
Drug-resistant epilepsy affects approximately one-third of patients and is often not amenable to resective surgery due to the bilateral nature of the epileptogenic network, multifocality, or localization of the seizure onset zone within eloquent cortical areas. In such cases, neuromodulation techniques are preferable,...