Author

D. Silva

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Open access Sep 2026

Dual antileishmanial and immunoregulatory activities of synthetic chalcones against Leishmania braziliensis.

Leishmaniasis remains a neglected tropical disease with limited therapeutic options and significant drug toxicity. In this study, two synthetic chalcones, (E)-1-(benzo[d][1,3]dioxol-5-yl)-3-(4-dimethylaminophenyl)prop-2-en-1-one (FER42) and (E)-1-(benzo[d][1,3]dioxol-5-yl)-3-(4-fluorophenyl)prop-2-en-1-one (FER45), wer...

Rebeca Pinheiro de Jesus Santana, Beatriz Cerqueira dos Santos, D. Silva et al. · Microbial Pathogenesis · 0 citations