Endometrial cancer is one of the gynecologic malignancies most strongly associated with obesity, yet the biological basis of this association extends beyond excess adiposity as a risk factor. Obesity reshapes the endometrial ecosystem through peripheral estrogen excess, progesterone imbalance, insulin resistance, adipo...
D. Simancas-Racines, Dolores Jima Gavilanes, Andri Matos et al.· Frontiers in Cell and Develo...· 0 citations
Adipose tissue expandability refers to the capacity of white adipose tissue to store excess energy safely while preserving metabolic homeostasis. This adaptive response takes place via both an increase in adipocyte number (hyperplasia) and size (hypertrophy). Healthy expansion requires coordinated angiogenesis, extrace...
Emilia Jiménez-Flores, C. Reytor-González, Dolores Jima Gavilanes et al.· Nutrients· 0 citations
Introduction Dengue is expanding beyond its traditional lowland range as rising temperatures may enable Aedes aegypti establishment at progressively higher altitudes. Ecuador, spanning sea level to above 4500 m, offers a natural altitudinal experiment, yet hospital-based evidence on the thermal drivers of Andean dengue...
Jaime Angamarca-Iguago, J. Cagua-Ordoñez, J. Parise-Vasco et al.· Frontiers in Epidemiology· 0 citations
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