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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

D. Speed

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Open access Sep 2026

Quantifying the genetic separability of disease subtypes

Genetic prediction of clinically defined disease subtypes could advance precision medicine, but polygenic risk scores (PRSs) often show limited ability to distinguish subtypes, either because the subtypes share genetic architecture or because available PRSs are inaccurate. We introduce GenSep, a statistical framework t...

C. Ning, J. Hof, D. Speed · 0 citations

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