Author

D. V. Tabakov

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Review Open access Oct 2026

The insulin gene in humans and mice: evolution, regulation, and sex-specific mechanisms of diabetes susceptibility

The insulin gene (INS) encodes a peptide hormone critical for glucose homeostasis, and its dysregulation underlies both type 1 and type 2 diabetes mellitus. This review compares the structural organization and functional regulation of the insulin gene in humans and mice, highlighting key species differences including t...

A. Mazloum, N. Batashkov, Veronika S. Ledyaeva et al. · Frontiers in Endocrinology · 0 citations

Review Open access Jul 2026

Biomarkers of treatment response in rheumatoid arthritis: from conventional markers to tissue immunophenotype

It is concluded that precision medicine in RA will require integrated biomarker panels combining clinical, pharmacological, molecular, and synovial tissue data, and the development of scalable, externally validated, and clinically interpretable models capable of assigning synovial endotypes and supporting mechanism-bas...

N. A. Batashkov, E. Gerasimova, D. Gerasimova et al. · Frontiers in Immunology · 0 citations