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Review Aug 2026

Engineered exosomes for CRISPR/Cas delivery to overcome oncogene-driven drug resistance.

The goal of this review is to outline a realistic pathway featuring proof-of-concept research, through discoveries to the creation of manufacturable, safe, and effective exosome/CRISPR therapeutics that can trigger durable therapeutic responses in resistant malignancies.

D. Uti · 0 citations
Review Aug 2026

Synthetic biology strategies for engineering microbial therapeutics in metabolic diseases and cancer.

This review highlights chassis selection, circuit architectures, applications for metabolic diseases and cancer, metabolic bottlenecks, and future directions for precision microbial therapeutics for metabolic disorders and oncology.

Boniface Adakole Onoja, S. A. Agada, Waheeb S. Aggad et al. · 0 citations