Somatic mosaicism is increasingly recognized as a fundamental feature of human biology, yet the detection of somatic mutations remains challenging. The Somatic Mosaicism across Human Tissues (SMaHT) Network conducted large-scale benchmarking experiments involving cell lines and donor tissues to evaluate sequencing tech...
A. Abyzov, Abhiram Natu, Adam Voshall et al.· Cell· 1 citation
ABSTRACT Cell state, growth, and mechanics are tightly connected properties underpinned by fundamental biological processes. Yet methods to quantify them simultaneously under physiologically relevant conditions, at resolutions sufficient to follow (sub)cellular processes, are still lacking. In particular, the correlati...
Ilaria Incaviglia, Giulia E. M. Ammirati, S. Herzog et al.· Advancement of science· 0 citations
ABSTRACT Our previous studies have shown that inoculation of primary endothelial cells with BKV results in a long-term persistent infection, with inoculated cultures surviving up to 60 days while producing low levels of infectious viral progeny. Unlike the permissive renal proximal tubule cells, infected endothelial ce...
Lindsay C. Colgan, Ping An, P. Cantalupo et al.· Journal of Virology· 0 citations
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