Open access
Aug 2026
Integrative analysis of scRNA-seq and bulk RNA-seq with machine learning develops a nucleotide metabolism–based prognostic model for ccRCC and reveals the function of IFI30
An NMRGs signature is developed that outperforms existing models and reveals that IFI30 promotes ccRCC malignant progression by regulating nucleotide metabolism, providing a new theoretical basis for prognostic assessment and metabolism-targeted therapy in ccRCC.
Qiao Lyu, Ping Li, Zhen-Xiong Ye et al.
· Frontiers in Oncology · 0 citations