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Author

Douglas Yee

2 papers indexed here

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Open access Oct 2026

Rilvegostomig Plus Trastuzumab-Deruxtecan for Early-Stage Breast Cancer

Importance The I-SPY2.2 trial tests personalized treatment strategies to improve outcomes while reducing exposure to standard chemotherapy in patients with high-risk early breast cancer (EBC). Objective To evaluate the efficacy and safety of trastuzumab-deruxtecan (T-DXd), an antibody drug conjugate targeting low ERBB2...

C. O'Sullivan, K. Kalinsky, C. Yau et al. · 0 citations
Open access Aug 2026

APOBEC3B mRNA Expression in Breast Cancer Correlates with Genomic Mutational Signatures

Despite advances in screening and treatment, breast cancer remains a leading cause of cancer-related mortality. APOBEC enzymes, particularly APOBEC3B (A3B), are upregulated in many cancers, contributing to a characteristic C-to-T mutational signature found in 30-50% of breast cancers. However, the relationship between...

J. Pardo, N. Temiz, Douglas Yee · 0 citations

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