Metabolomic Changes in Biofilm of Pseudomonas aeruginosa Under Early-Stage Tobramycin Treatment Identified by 2D NMR-Based COLMARq
Biofilms are estimated to account for a large proportion of persistent microbial infections and are associated with substantial mortality in hospitals. Pseudomonas aeruginosa biofilms exhibit higher resistance to antibiotics compared to their planktonic growth form, making them difficult to eradicate and contributing...