Indigo is an important biobased colorant used in textile dyeing and as a precursor for blue food colorants; however, its microbial production is often limited by cytotoxicity and intracellular accumulation of insoluble products. Here, we established a systems-level host engineering framework in Escherichia coli to impr...
Heng Hu, Meng-Ying Jiang, Yan Zheng et al.· Journal of Agricultural and...· 0 citations
Hydrophobic microenvironment engineering might represent a promising strategy for modulating proton transfer and provide a potential framework for improving the activity of ZEN lactonases for food and feed detoxification.
Bin-Bin Ouyang, Zhao Huang, Chen-Shuo Song et al.· Journal of Agricultural and...· 0 citations
2'-Fucosyllactose (2'-FL), the most abundant human milk oligosaccharide (HMO), has attracted considerable interest for its prebiotic and immunomodulatory functions, with broad applications in infant nutrition. In this study, we report the development of a high-yield, genome-integrated 2'-FL-producing strain based on Es...
Rou-Lin Chen, Longhao Yang, Hao Wang et al.· Enzyme and Microbial Technol...· 0 citations
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