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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Da Yang

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2 papers indexed here

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Open access Aug 2026

Drosophila Rumpelstiltskin regulates Polycomb cis and trans interactions and Homie barrier activity

Three-dimensional genome organization is maintained in part by chromatin insulators, DNA–protein complexes that create boundaries between active and inactive chromatin and regulate enhancer-promoter interactions. In Drosophila, the Homing insulator at eve (Homie) sequence prevents repressive Polycomb (PcG) chromatin at...

Savanna Lyda, C. McManus, Juan Manuel Caravaca et al. · 0 citations
Review Open access Sep 2026

Transcription and Three‐Dimensional Genome Organization: Cause, Consequence, or Coordination?

Transcription and three‐dimensional (3D) genome organization are closely coupled, but their precise relationship remains unresolved. Evidence from perturbation, imaging, and modeling studies suggests that transcription is not strictly required for the establishment of large‐scale genome features such as compartments an...

Da Yang, Elissa P. Lei · 0 citations

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