Jul 2026
Discovery of Novel LRPPRC Inhibitors Featuring a Biphenyl-Acylhydrazone Scaffold with Potent Broad-Spectrum Antitumor Activity.
Novel biphenyl-acylhydrazone LRPPRC inhibitors are developed as potent antitumor agents acting via OXPHOS modulation, providing a valuable lead compound for cancer therapy.
Hairu Ren, Jie Liu, Dachi Wang et al.
· Journal of Medicinal Chemist... · 0 citations