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Author

Dagmara Otto-Ślusarczyk

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2 papers indexed here

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Review Open access Sep 2026

Pharmacological targeting of ferroptosis in cancer: mechanisms, tumor immunity, and translational challenges.

Ferroptosis is an iron-dependent form of regulated cell death driven by phospholipid peroxidation and the failure of cellular antioxidant defenses. Its close integration with iron metabolism, lipid remodeling, and redox homeostasis has identified ferroptosis as a potentially exploitable vulnerability in cancer. This re...

A. Zdanowicz, B. Pradhan, B. Pyrzyńska et al. · 0 citations
Open access Jul 2026

In Silico Design and Evaluation of Quinone Methide Oxime Derivatives as Potential Non-Covalent Steroid Sulfatase Inhibitors

Steroid sulfatase (STS) plays a crucial role in intratumoral estrogen biosynthesis and represents an attractive therapeutic target in estrogen receptor-positive breast cancer. In this study, a new series of potential STS inhibitors based on the quinone methide oxime scaffold, precisely 2-(4-hydroxyiminocyclohexa-2,5-di...

D. Khylyuk, O. M. Demchuk, Serhii Holota et al. · 0 citations

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